Base de datos : IBECS
Búsqueda : "1139-6709" [ISSN]
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Id: 171333
Autor: Cava, Felipe.
Título: Divergent functional roles of D-amino acids secreted by Vibrio cholera
Fuente: Int. microbiol;20(3):149-150, sept. 2017.
Idioma: en.
doi: 10.2436/20.1501.01.296.
Resumen: The L-forms of amino acids are used in all kingdoms of life to synthesize proteins. However, the bacterium Vibrio cholerae, the causative agent of cholera, produces D-amino acids which are released to the environment at millimolar concentrations. We baptized these D-amino acids as non-canonical D-amino acids (NCDAAs) since they are different from those (i.e. D-alanine and D-glutamate) normally present in the bacterial cell wall. In V. cholerae, production of NCDAAs relies on the BsrV enzyme, a periplasmic broad spectrum racemase. BsrV multispecific activity, produces of a wide range of distinct D-amino acids. Using a combination of genetics and molecular physiology approaches we have demonstrated that NCDAAs target different cellular processes which may function as part of a cooperative strategy in vibrio communities to protect non-producing members from competing bacteria. Because NCDAA production is widespread in bacteria, we anticipate that NCDAAs are relevant modulators of microbial subpopulations in diverse ecosystems (AU)

No disponible
Descriptores: aminoácidos/análisis
Vibrio cholerae/aislamiento & purificación
cólera/etiología
alanina/análisis
pared celular/microbiología
-periplasma/microbiología
metionina/análisis
metionina/aislamiento & purificación
arginina/análisis
Límites: humanos
masculino
femenino
Tipo de Publicación: revisión
Responsable: BNCS


  2 / 508 IBECS  
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Id: 171332
Autor: Escudero, Jose Antonio; Mazel, Didier.
Título: Genomic Plasticity of Vibrio cholerae
Fuente: Int. microbiol;20(3):138-148, sept. 2017. ilus.
Idioma: en.
doi: 10.2436/20.1501.01.295.
Resumen: Vibrio cholerae is one of the deadliest pathogens in the history of humankind. It is the causative agent of cholera, a disease characterized by a profuse and watery diarrhoea that still today causes 95.000 deaths worldwide every year. V. cholerae is a free living marine organism that interacts with and infects a variety of organisms, from amoeba to humans, including insects and crustaceans. The complexity of the lifestyle and ecology of V. cholerae suggests a high genetic and phenotypic plasticity. In this review, we will focus on two peculiar genomic features that enhance genetic plasticity in this bacterium: the division of its genome in two different chromosomes and the presence of the superintegron, a gene capture device that acts as a large, low-cost memory of adaptive functions, allowing V. cholerae to adapt rapidly (AU)

No disponible
Descriptores: Vibrio cholerae/genética
Vibrio cholerae/aislamiento & purificación
factores de iniciación procarióticos/aislamiento & purificación
cólera/microbiología
diarrea/microbiología
-cólera/etiología
diarrea/etiología
estilo de vida
genoma bacteriano/genética
Límites: humanos
masculino
femenino
Tipo de Publicación: revisión
Responsable: BNCS


  3 / 508 IBECS  
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Id: 171331
Autor: Kostiuk, Benjamin; Unterweger, Daniel; Provenzano, Daniel; Pukatzki, Stefan.
Título: T6SS intraspecific competition orchestrates Vibrio cholerae genotypic diversity
Fuente: Int. microbiol;20(3):130-137, sept. 2017. ilus.
Idioma: en.
doi: 10.2436/20.1501.01.294.
Resumen: Vibrio cholerae is a diverse species that inhabits a wide range of environments from copepods in brackish water to the intestines of humans. In order to remain competitive, V. cholerae uses the versatile type-VI secretion system (T6SS) to secrete anti-prokaryotic and anti-eukaryotic effectors. In addition to competing with other bacterial species, V. cholerae strains also compete with one another. Some strains are able to coexist, and are referred to as belonging to the same compatibility group. Challenged by diverse competitors in various environments, different V. choleare strains secrete different combination of effectors - presumably to best suit their niche. Interestingly, all pandemic V. cholerae strains encode the same three effectors. In addition to the diversity displayed in the encoded effectors, the regulation of V. cholerae also differs between strains. Two main layers of regulation appear to exist. One strategy connects T6SS activity with behavior that is suited to fighting eukaryotic cells, while the other is linked with natural competence - the ability of the bacterium to acquire and incorporate extracellular DNA. This relationship between bacterial killing and natural competence is potentially a source of diversification for V. cholerae as it has been shown to incorporate the DNA of cells recently killed through T6SS activity. It is through this process that we hypothesize the transfer of virulence factors, including T6SS effector modules, to happen. Switching of T6SS effectors has the potential to change the range of competitors V. cholerae can kill and to newly define which strains V. cholerae can co-exist with, two important parameters for survival in diverse environments (AU)

No disponible
Descriptores: Vibrio cholerae/genética
Vibrio cholerae/aislamiento & purificación
Eukaryota/aislamiento & purificación
factores de iniciación procarióticos/aislamiento & purificación
sistemas de secreción bacterianos/análisis
sistemas de secreción de tipo VI/aislamiento & purificación
-sistemas de secreción bacterianos/clasificación
Límites: humanos
masculino
femenino
Tipo de Publicación: revisión
Responsable: BNCS


  4 / 508 IBECS  
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Id: 171330
Autor: Espinosa, Elena; Barre, François-Xavier; Galli, Elisa.
Título: Coordination between replication, segregation and cell division in multi-chromosomal bacteria: lessons from Vibrio cholera
Fuente: Int. microbiol;20(3):121-129, sept. 2017. ilus.
Idioma: en.
doi: 10.2436/20.1501.01.293.
Resumen: Bacteria display a highly flexible cell cycle in which cell division can be temporally disconnected from the replication/segregation cycle of their genome. The accuracy of genetic transmission is enforced by restricting the assembly of the cell division apparatus to the low DNA-density zones that develop between the regularly spaced nucleoids originating from the concurrent replication and segregation of genomic DNA. In most bacteria, the process is simplified because the genome is encoded on a single chromosome. This is notably the case in Escherichia coli, the most well studied bacterial model organism. However, ~10% of bacteria have domesticated horizontally acquired mega-plasmids into extra-numerous chromosomes. Most of our current knowledge on the cell cycle regulation of multi-chromosomal species derives from the study of replication, segregation and cell division in Vibrio cholerae, the agent of the deadly epidemic human diarrheal disease cholera. A nicety of this model is that it is closely related to E. coli in the phylogenetic tree of bacteria. Here, we review recent findings on the V. cholerae cell cycle in the context of what was previously known on the E. coli cell cycle (AU)

No disponible
Descriptores: Vibrio cholerae/citología
Vibrio cholerae/genética
ciclo celular
Escherichia coli/aislamiento & purificación
replicación del ADN
segregación cromosómica
división celular
-infecciones por Escherichia coli/microbiología
Límites: humanos
masculino
femenino
Tipo de Publicación: revisión
Responsable: BNCS


  5 / 508 IBECS  
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Id: 171329
Autor: Yen, Minmin; Camilli, Andrew.
Título: Mechanisms of the evolutionary arms race between Vibrio cholerae and Vibriophage clinical isolates
Fuente: Int. microbiol;20(3):116-120, sept. 2017. tab.
Idioma: en.
doi: 10.2436/20.1501.01.292.
Resumen: This review highlights recent findings on the evolutionary arms race between the causative agent of cholera Vibrio cholerae and virulent bacteriophages (phages) ICP1, ICP2, and ICP3 isolated from cholera patient stool samples. We discuss mechanisms of phage resistance such as a unique phage-inhibitory chromosomal island and mutations that affect phage receptor expression. We also discuss the molecular characterization of ICP1 and its unique CRISPR-Cas system, which it uses to combat the phage-inhibitory chromosomal island. The role of phages in the life cycle of V. cholerae has been increasingly recognized and investigated in the past decade. This article will review hypotheses as to how the predator-prey relationship may have an impact on infections within individuals and on the self-limiting nature of cholera epidemics. In addition, we put forth a strategy of using phages as an intervention to reduce household transmission of cholera within a community (AU)

No disponible
Descriptores: Vibrio cholerae/aislamiento & purificación
bacteriófagos/aislamiento & purificación
tipificación de bacteriófagos/clasificación
cólera/diagnóstico
cólera/microbiología
-heces/microbiología
Límites: humanos
masculino
femenino
Tipo de Publicación: revisión
Responsable: BNCS


  6 / 508 IBECS  
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Id: 171328
Autor: Tarequl Islam, Mohammad; Alam, Munirul; Boucher, Yan.
Título: Emergence, ecology and dispersal of the pandemic generating Vibrio cholerae lineage
Fuente: Int. microbiol;20(3):106-115, sept. 2017. ilus.
Idioma: en.
doi: 10.2436/20.1501.01.291.
Resumen: Although cholera is an ancient disease that first arose at least half a millennium ago, it remains a major health threat globally. Its pandemic form is caused by strains from a single lineage of the bacterium Vibrio cholerae. The ancestor of this lineage harbored several distinctive characteristics, the most notable being the O1 antigen polysaccharide. This lineage generated two biotypes, first Classical, responsible for six pandemics, and later El Tor, responsible for the seventh and ongoing pandemic. Just as El Tor replaced Classical as the main cause of outbreaks in the last fifty years, several variants of El Tor have evolved and displaced their predecessors worldwide. Understanding the ecology, evolution and dispersal of pandemic V. cholerae is central to studying this complex disease with environmental reservoirs. Here, we present recent advancements of our knowledge on the emergence and spread of the pandemic generating lineage of V. cholerae in the light of established eco-evolutionary observations. Specific ecological interactions shape seasonal cholera, playing a role in the abundance and distribution of its causative agent. Both species-specific and lineage-specific genetic determinants play a role in the ability of V. cholerae strains to cause pandemics with seasonal outbreaks, having evolved gradually over centuries. On the basis of the current understanding, we outline future threats and changes in biogeographical and genomic-based investigation strategies to combat this global problema (AU)

No disponible
Descriptores: vectores de enfermedades
cólera/epidemiología
cólera/microbiología
Vibrio cholerae/aislamiento & purificación
Vibrio cholerae/patogenicidad
-Vibrio cholerae/genética
urgencias/epidemiología
Límites: humanos
masculino
femenino
Tipo de Publicación: revisión
Responsable: BNCS


  7 / 508 IBECS  
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Id: 164605
Autor: Centers for Disease Control and Prevention.
Título: CDC Report on the Potential Exposure to Anthrax
Fuente: Int. microbiol;17(2):119-129, jun. 2014.
Idioma: en.
doi: 10.2436/20.1501.01.214.
Resumen: The Centers for Disease Control and Prevention (CDC) conducted an internal review of an incident that involved an unintentional release of potentially viable anthrax within its Roybal Campus, in Atlanta, Georgia. On June 5, 2014, a laboratory scientist in the Bioterrorism Rapid Response and Advanced Technology (BRRAT) laboratory prepared extracts from a panel of eight bacterial select agents, including Bacillus anthracis (B. anthracis), under biosafety level (BSL) 3 containment conditions. These samples were being prepared for analysis using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry, a technology that can be used for rapid bacterial species identification (AU)

No disponible
Descriptores: ántrax/microbiología
Bacillus anthracis/fisiología
-ántrax/prevención & control
laboratorios
Bacillus anthracis/química
Bacillus anthracis/genética
Center for Disease Control and Prevention (U.S.)
espectrometría de masas
salud laboral
contención de riesgos biológicos
Estados Unidos
Límites: humanos
Responsable: BNCS


  8 / 508 IBECS  
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Id: 164594
Autor: Finch, Janet; Bell, Simon; Bellingan, Laura; Campbell, Robert; Donnelly, Peter; Gardner, Rita; Hall, Martin; Hall, Steven; Kiley, Robert; Stelt, Wim van der; Sweeney, David; Sykes, Phil; Tickell, Adam; Wissenburg, Astrid; Egginton, Ron; Jubb, Michael.
Título: Accessibility, sustainability, excellence: how to expand access to research publications. Executive summary
Fuente: Int. microbiol;16(2):125-132, jun. 2013.
Idioma: en.
doi: 10.2436/20.1501.01.187.
Resumen: No disponible

No disponible
Descriptores: acceso a la información
investigación biomédica
Publicaciones/economía
-motor de búsqueda/economía
directrices como asunto
publicaciones periódicas como asunto
sistemas en línea/economía
Límites: humanos
Responsable: BNCS


  9 / 508 IBECS  
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Id: 164540
Autor: Bañeras, Lluís; Ruiz-Rueda, Olaya; López-Flores, Rocío; Quintana, Xavier D; Hallin, Sara.
Título: The role of plant type and salinity in the selection for the denitrifying community structure in the rhizosphere of wetland vegetation
Fuente: Int. microbiol;15(2):89-99, jun. 2012. ilus, tab, graf.
Idioma: en.
doi: 10.2436/20.1501.01.162.
Resumen: Coastal wetlands, as transient links from terrestrial to marine environments, are important for nitrogen removal by denitrification. Denitrification strongly depends on both the presence of emergent plants and the denitrifier communities selected by different plant species. In this study, the effects of vegetation and habitat heterogeneity on the community of denitrifying bacteria were investigated in nine coastal wetlands in two preserved areas of Spain. Sampling locations were selected to cover a range of salinity (0.81 to 31.3 mS/cm) and nitrate concentrations (0.1 to 303 μM NO3-), allowing the evaluation of environmental variables that select for denitrifier communities in the rhizosphere of Phragmites sp., Ruppia sp., and Paspalum sp. Potential nitrate reduction rates were found to be dependent on the sampling time and plant species and related to the denitrifier community structure, which was assessed by terminal restriction fragment length polymorphism analysis of the functional genes nirS, nirK and nosZ. The results showed that denitrifier community structure was also governed by plant species and salinity, with significant influences of other variables, such as sampling time and location. Ruppia sp. and Phragmites sp. selected for certain communities, whereas this was not the case for Paspalum sp. The plant species effect was strongest on nirK-type denitrifiers, whereas water carbon content was a significant factor defining the structure of the nosZ-harboring community. The differences recognized using the three functional gene markers indicated that different drivers act on denitrifying populations capable of complete denitrification, compared to the overall denitrifier community. This finding may have implications for emissions of the greenhouse gas nitrous oxide (AU)

No disponible
Descriptores: microbiología del suelo
ecosistema
Bacteria/crecimiento & desarrollo
plantas/microbiología
rizosfera
desnitrificación/genética
-España
salinidad
estadísticos no paramétricos
humedales
polimorfismo de longitud del fragmento de restricción
Responsable: BNCS


  10 / 508 IBECS  
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Id: 164539
Autor: Toro, María de; Sáenz, Yolanda; Cercenado, Emilia; Rojo-Bezares, Beatriz; García-Campello, Marta; Undabeitia, Esther; Torres, Carmen.
Título: Genetic characterization of the mechanisms of resistance to amoxicillin/clavulanate and third-generation cephalosporins in Salmonella enterica from three Spanish hospitals
Fuente: Int. microbiol;14(3):173-181, sept. 2011. tab, ilus.
Idioma: en.
doi: 10.2436/20.1501.01.146.
Resumen: The mechanisms of antimicrobial resistance were characterized in 90 Salmonella enterica isolates either resistant or with intermediate resistance to amoxicillin/clavulanate (AMC(R/I)) or resistant to third-generation cephalosporins (C3G(R)). These isolates were recovered in three Spanish hospitals during 2007-2009. The C3G(R) phenotype was expressed by three isolates that carried the following extended-spectrum β-lactamase genes: phage-associated bla(CTX M-10) in S. Virchow, bla(CTX-M-14a) surrounded by ISEcp1 and IS903 in S. Enteritidis, and bla(CTX-M-15) linked to ISEcp1 and orf477 in S. Gnesta (first description in this serotype). The AMC(R/I) phenotype was found in 87 isolates (79 S. Typhimurim, 7 S. Enteritidis, and one S. Thompson). The bla(PSE-1) gene, followed by bla(OXA-1) was mostly found among S. Typhimurim, and the bla(TEM-1) gene among S. Enteritidis. Three different gene combinations [bla(PSE-1) +floR+aadA2+sul+tet(G); bla(OXA-1) +catA+aadA1/strA-strB+sul+tet(B) and bla(TEM-1) + cmlA1+aadA/strA-strB+sul+tet(A)/tet(B) genes] were associated with the ampicillin-chloramphenicol-streptomycin-sulfonamides-tetracycline phenotype in 68 AMC(R/I) S. enterica isolates. Class 1 integrons were observed in 79% of the isolates and in most of them (45 isolates) two integrons including the aadA2 and bla(PSE-1) gene cassettes, respectively, were detected. The bla(OXA-1) +aadA1 arrangement was detected in 23 isolates, and the aac(6')-Ib-cr+bla(OXA-1) +catB3+arr3 in another one. Non-classic class 1 integrons were found in three isolates: dfrA12+orfF+aadA2+cmlA1+aadA1 (1 isolate), dfrA12+orfF+aadA2+ cmlA1+aadA1+qacH+IS440+sul3 (1 isolate) and dfrA12+orfF+aadA2+cmlA1+aadA1+qacH+IS440+ sul3+orf1+mef(B)Δ-IS26 (1 isolate). Taken together, these results underline the need for clinical concern regarding β-lactam resistance in Salmonella and thus for continuous monitoring (AU)

No disponible
Descriptores: integrones/genética
infección hospitalaria/tratamiento farmacológico
ácido clavulánico/administración & dosificación
cefalosporinas/administración & dosificación
Salmonella enterica/genética
resistencia a beta-lactámicos/genética
infecciones por Salmonella/tratamiento farmacológico
-España
combinación de amoxicilina clavulanato potásico
penicilinasa/genética
antibacterianos
electroforesis en gel de campo pulsado
Límites: humanos
Responsable: BNCS



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