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Id: 232352
Autor: Martin-Fumadó, Carles; Pujol-Robinat, Amadeo; Arimany-Manso, Josep.
Título: The Present Legal Status Regarding the Utilization of Mechanical or Pharmacological Restraints in Psychiatric and Social-Health Settings
Fuente: Actas esp. psiquiatr;52(2):189-191, 2024.
Idioma: en.
doi: 10.62641/aep.v52i2.1660.
Descriptores: trastornos mentales/farmacoterapia
tratamiento psiquiátrico involuntario/legislación & jurisprudencia
agitación psicomotora/farmacoterapia
agitación psicomotora/prevención & control
Límites: seres humanos
Tipo de Publicación: carta
Responsable: ES15.1 - BNCS


  2 / 1235 IBECS  
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Id: 232351
Autor: Wu, Yuejing; He, Qian; Zhang, Li; Li, Tao; Luo, Fugang.
Título: Successful Recovery of a Catatonic Patient with Severe Pneumonia and Respiratory Failure: Modified Electroconvulsive Therapy Following Tracheotomy
Fuente: Actas esp. psiquiatr;52(2):183-188, 2024. ilus.
Idioma: en.
doi: 10.62641/aep.v52i2.1528.
Resumen: Backgroud: Catatonia encompasses a group of severe psychomotor syndromes affecting patients' motor, speech, and complex behaviors. Common features include rigidity, reduced mobility, speech, sputum production, defecation, and eating. Risks associated with catatonia, such as increased muscle tension and reduced swallowing and coughing reflexes, along with risks from therapeutic approaches like prolonged bed rest and sedative drugs, can elevate the risk of aspiration pneumonia, severe pneumonia, and acute respiratory failure. These complications significantly impede catatonia treatment, leading to poor prognosis and jeopardizing patient safety. Case Description: In this report, we present a case of catatonia complicated by severe pneumonia and respiratory failure, successfully managed with modified electroconvulsive therapy alongside tracheotomy. We hope this case provides valuable insights for psychiatrists encountering similar scenarios, facilitating the development of rational therapeutic strategies for prompt improvement of patient condition. (AU)
Descriptores: esquizofrenia catatónica/diagnóstico por imagen
esquizofrenia catatónica/diagnóstico
esquizofrenia catatónica/terapia
terapia electroconvulsiva
-neumonía
insuficiencia respiratoria
traqueotomía
Límites: seres humanos
femenino
persona de mediana edad
Tipo de Publicación: informes de casos
Responsable: ES15.1 - BNCS


  3 / 1235 IBECS  
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Id: 232350
Autor: Álamo, Cecilio; Sáiz Ruiz, Jerónimo; Zaragozá Arnáez, Cristina.
Título: Orexinergic Receptor Antagonists as a New Therapeutic Target to Overcome Limitations of Current Pharmacological Treatment of Insomnia Disorder
Fuente: Actas esp. psiquiatr;52(2):172-178, 2024. graf.
Idioma: en.
doi: 10.62641/aep.v52i2.1659.
Resumen: Insomnia disorder is a common condition that is considered a risk factor for multiple physical and mental disorders, contributing to reduced quality of life and increased healthcare expenditures. Although cognitive behavioral therapy (CBT) is typically recommended as the primary intervention, its accessibility is hindered by limited resources, prompting the prevalent use of pharmacological interventions as the primary treatment in clinical settings. This study reviews the benefits and risks of current pharmacological treatments for insomnia, with special reference to the orexinergic system as a novel therapeutic target for treatment. The prescription of GABAergic mechanism enhancers (benzodiazepine (BZD) and ôZ drugsö) has shown efficacy in short-term insomnia treatment (less than 4 weeks), however, concerns arise regarding their long-term effectiveness, unfavorable tolerability and safety profiles, including the potential for dependency. Drugs with antihistamine properties, including certain antidepressants and antipsychotics, exhibit short-term efficacy but have documented tolerability limitations, especially in the elderly. The use of melatonin, available in various formulations, lacks comprehensive long-term data. Dual orexin receptor antagonists (DORAs) such as daridorexant, lemborexant, and suvorexant, represent a novel approach to insomnia treatment by inhibiting wakefulness rather than enhancing sedation. As the only DORA approved for insomnia treatment by the European Medicines Agency (EMA) and Food and Drug Administration (FDA), daridorexant has demonstrated sustained efficacy over a 12-month period, improving nocturnal sleep parameters and daytime functionality, with a favorable safety and tolerability profile. (AU)
Descriptores: trastornos de la iniciación y mantenimiento del sueño
benzodiacepinas
orexinas
-antagonistas de los receptores de orexina
Límites: seres humanos
Tipo de Publicación: revisión
Responsable: ES15.1 - BNCS


  4 / 1235 IBECS  
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Id: 232349
Autor: Wei, Bo; Xu, Yiqin; Du, Ye; Zhou, Jie; Zhong, Fangfang; Wu, Chenglong; Lou, Yiping.
Título: Feasibility of Using Magnetic Resonance Spectroscopy Test Biomarkers to Diagnose Alzheimer's Disease: Systematic Evaluation and Meta-Analysis
Fuente: Actas esp. psiquiatr;52(2):161-167, 2024. tab, graf.
Idioma: en.
doi: 10.62641/aep.v52i2.1552.
Resumen: Background: Alzheimer's disease (AD) is the leading cause of dementia, resulting in impairments in memory, cognition, decision-making, and social skills. Thus, accurate preclinical diagnosis of Alzheimer's disease is paramount. The identification of biomarkers for Alzheimer's disease through magnetic resonance spectroscopy (MRS) represents a novel adjunctive diagnostic approach.Objective: This study conducted a meta-analysis of the diagnostic results of this technology to explore its feasibility and accuracy.Methods: PubMed, Cochrane Library, EMBASE, and Web of Science databases were searched without restrictions, with the search period extending up to July 31, 2022. The search strategy employed a combination of subject headings and keywords. All retrieved documents underwent screening by two researchers, who selected them for meta-analysis. The included literature was analyzed using Review Manager 5.4 software, with corresponding bias maps, forest plots, and summary receiver operating characteristic (SROC) curves generated and analyzed.Results: A total of 344 articles were retrieved initially, with 11 articles meeting the criteria for inclusion in the analysis. The analysis encompassed data from approximately 1766 patients. In the forest plot, both sensitivity (95% CI) and specificity (95% CI) approached 1. Examining the true positive rate, false positive rate, true negative rate, and false negative rate, all studies on the summary receiver operating characteristic (SROC) curve clustered in the upper left quadrant, suggesting a very high accuracy of biomarkers detected by MRS for diagnosing Alzheimer's disease.Conclusion: The detection of biomarkers by MRS demonstrates feasibility and high accuracy in diagnosing AD. This technology holds promise for widespread adoption in the clinical diagnosis of AD in the future. (AU)
Descriptores: espectroscopia de resonancia magnética
biomarcadores
enfermedad de Alzheimer/diagnóstico
Límites: seres humanos
Tipo de Publicación: metaanálisis
revisión sistemática
Responsable: ES15.1 - BNCS


  5 / 1235 IBECS  
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Id: 232348
Autor: Bartolomé del Pino, Leticia E; Zanón-Moreno, Vicente.
Título: Systematic Review on the Relationship between Toxoplasmosis and Mental Disorders
Fuente: Actas esp. psiquiatr;52(2):149-160, 2024. tab, graf.
Idioma: en.
doi: 10.62641/aep.v52i2.1658.
Resumen: Background: Toxoplasmosis is a worldwide parasitic zoonosis caused by the protozoan Toxoplasma gondii. In cases of vertical infection, and in immunosuppressed people by the human immunodeficiency virus (HIV) serious clinical conditions may appear, while immunocompetent people do not present symptoms. However, T. gondii infection has been linked to several mental disorders for decades.Objective: To substantiate the possible relationship between T. gondii and mental disorders and suggest control and prevention strategies.Material and Methods: A systematic review has been carried out to analyze the relationship between T. gondii exposure (presence of IgG) and the onset of mental disorders in minors and adults. The etiopathogenic mechanisms described by the authors have also been included and the systems of surveillance, prevention and control of infection have been evaluated.Results: Several processes linked to the presence of cysts and the reactivation of the parasite in certain situations produce an immune and inflammatory response. Also, direct and indirect actions on different neurotransmitters. These mechanisms, together with other environmental and genetic factors, would predispose to different psychiatric pathologies.Conclusions: Due to the limits of the study, no conclusions can be drawn in childhood and adolescence. However, the results of this systematic review show a possible association of schizophrenia, bipolar disorder and compulsive disorder with T. gondii infection in adults. There is a need to improve control, integrated surveillance and extend prevention measures to the entire population. (AU)
Descriptores: toxoplasmosis
trastornos mentales
neuropatología
prevención primaria
vigilancia en salud pública
Límites: seres humanos
Tipo de Publicación: revisión sistemática
Responsable: ES15.1 - BNCS


  6 / 1235 IBECS  
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Id: 232347
Autor: Li, Xiumei; Gao, Wei; Yu, Jie; Mao, Yanling; Gu, Haihong; Li, Fang; Ren, Dongmei.
Título: Mental Health and Quality of Life in Chronic Kidney Disease Patients with Mild-to-Moderate Depression: A Retrospective Cohort Study of Mindfulness-Based Stress Reduction Therapy
Fuente: Actas esp. psiquiatr;52(2):138-148, 2024. tab, graf.
Idioma: en.
doi: 10.62641/aep.v52i2.1600.
Resumen: Background: Chronic kidney disease (CKD) patients may experience pessimism, and even despair, due to long-term nature of the condition, which increases the risk of depression. Mindfulness-based stress reduction (MBSR) can relieve depression. This retrospective cohort study aimed to investigate the effects of MBSR on mental health and quality of life in CKD patients with mild-to-moderate depression, so as to provide guidance for clinical nursing programs. Methods: The clinical data of 100 CKD patients with mild-to-moderate depression who were treated in Jiading District Central Hospital Affiliated Shanghai University of Medicine & Health Sciences from January 2021 to March 2023 were retrospectively analyzed. Based on nursing method received, the patients were divided into the conventional group (conventional management) and the MBSR group (MBSR therapy was implemented in addition to conventional management). After matching, there were 35 cases in each group. The scores for the self-rating depression scale (SDS), Connor-Davidson Resilience Scale (CD-RISC), Five-factor Mindfulness Questionnaire (FFMQ), Pittsburgh Sleep Quality Index (PSQI), and 36-item Short Form Health Survey (SF-36) were compared between the two groups. Results: After management, the SDS and PSQI scores of the MBSR group were lower than those of the conventional group, and the CD-RISC, FFMQ and SF-36 scores were higher than those of the conventional group (p < 0.05). Conclusion: MBSR can improve the mental health, sleep quality, and quality of life of CKD patients with mild-to-moderate depression, and improve psychological resilience and mindfulness. (AU)
Descriptores: insuficiencia renal crónica/psicología
salud mental
calidad de vida
atención plena
-estudios retrospectivos
estudios de cohortes
SUFRIMIENTO PSICOLOGICO
Tipo de Publicación: informes de casos
Responsable: ES15.1 - BNCS


  7 / 1235 IBECS  
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Id: 232346
Autor: Qiang, Yueke; Yang, Wenjian; Yang, Bing.
Título: Psychological Stress Analysis to Evaluate the Effects of Transcranial Magnetic Stimulation on Mood Regulation and Quality of Life in Patients with Bipolar Disorder
Fuente: Actas esp. psiquiatr;52(2):130-137, 2024. tab.
Idioma: en.
doi: 10.62641/aep.v52i2.1555.
Resumen: Objective: To explore the impact of transcranial magnetic stimulation on emotion regulation and quality of life in patients with bipolar disorder (BD) and to evaluate the effectiveness of the mental stress analyzer.Methods: Patients with BD admitted to our hospital from August 2022 to August 2023 were retrospectively selected. For the present study, 60 patients who received drug therapy served as the control group, and the other 60 patients who received repeated transcranial stimulation on this basis served as the observation group. The heart rate variability (HRV) of the two groups of patients was detected by a mental stress analyzer/HRV analysis system. Hamilton Depression Rating Scale (HAMD), Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS) were used to evaluate the mental state of the two groups of patients. The quality of life of the two groups was assessed using the Comprehensive Quality of Life Questionnaire 74 (GQOLI-74). Clinical effectiveness global rating scale-illness severity (CGI-SI) was used to evaluate the clinical symptoms of the two groups of patients, and the incidence of adverse reactions was calculated.Results: In comparison to the control group, the high-frequency power (HF) of the patients demonstrated an elevation in the observation group, and the low-frequency power (LF) and LF/HF were significantly reduced (p < 0.05). The standard deviation of NN intervals (SDNN), standard deviation of all five-minute NN intervals (SDANN), root mean square of successive differences (rMSSD), and percent RR intervals with a difference in duration higher than 50 ms (PNN50) of patients in the observation group showed a notable increase compared to the control group (p < 0.05). Compared with the control group, the HAMD, SAS, and SDS scores of the patients in the observation group demonstrated a substantial decline relative to the control group (p < 0.05). , ... Conclusions: ... (AU)
Descriptores: estrés psicológico
estimulación magnética transcraneal
afecto
calidad de vida
trastorno bipolar
Límites: seres humanos
masculino
femenino
adulto
Tipo de Publicación: informes de casos
Responsable: ES15.1 - BNCS


  8 / 1235 IBECS  
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Id: 232345
Autor: Chen, Peipei; Lin, Dandan.
Título: Solution-Focused Group Counseling on Mental States in Hemodialysis Patients with Anxiety
Fuente: Actas esp. psiquiatr;52(2):122-129, 2024. tab.
Idioma: en.
doi: 10.62641/aep.v52i2.1562.
Resumen: Background: Hemodialysis patients usually suffer from anxiety due to physical and social factors, which belongs to a kind of psychological disorder, easily contributing to the decrease of patients' adherence to the treatment, and seriously affecting the patients' health status and quality of life. Solution-focused group counseling (SFGC) is a kind of psychotherapy proven to improve emotional problems in many fields. Still, the application of this therapy is rare in medical situations. This retrospective study aims to analyze the application of SFGC and probe into the effects on mental states in hemodialysis patients with anxiety. Methods: From January 2022 to February 2023, 212 patients with hemodialysis and anxiety admitted to our hospital were selected, and 9 patients who did not meet the inclusion criteria were excluded. Finally, 203 patients were included in this retrospective study. According to different clinical management methods, 102 patients receiving routine management were classified as the control group (CG), and 101 patients receiving SFGC on the basis of routine management were included in the observation group (OG). The scores of the self-perceived burden scale (SPBS), medical coping modes questionnaire (MCMQ), and self-rating anxiety scale (SAS) of the two groups were collected. The data collected were calculated and processed by software SPSS 26.0, and the effects of different managements on the mental states of patients with hemodialysis and anxiety were compared. Results: After management, the scores of SPBS in both groups were lower than those before management, and the score in OG was significantly lower than the CG (p < 0.001). After management, the confrontation scores increased, the avoidance and resignation scores decreased in the MCMQ of the two groups, and the scores in the OG changed significantly (p < 0.001). ... (AU)
Descriptores: CITAS MEDICAS COMPARTIDAS
salud mental
diálisis renal/psicología
ansiedad/psicología
Límites: seres humanos
masculino
femenino
persona de mediana edad
anciano
Tipo de Publicación: informes de casos
Responsable: ES15.1 - BNCS


  9 / 1235 IBECS  
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Id: 232344
Autor: Duan, Wenrong; Huang, Jian; Huang, Qiuling; Dong, Birong.
Título: Relationship between Pain and Dementia: The Mediating Effect of Depression among Chinese Elderly
Fuente: Actas esp. psiquiatr;52(2):114-121, 2024. tab, graf.
Idioma: en.
doi: 10.62641/aep.v52i2.1530.
Resumen: Background: Chronic pain poses a significant problem for older adults and may potentially impact cognitive function. This study aimed to examine the cross-sectional relationship between pain severity and cognitive function in elderly individuals residing in the community. Additionally, this study sought to examine the mediating effect of depression on the relationship between pain and dementia. Methods: The study sample was derived from the 2018 China Health and Aging Longitudinal Study (CHARLS), comprising cross-sectional data from 4559 community residents aged 65 years or older. The primary outcome assessed was the occurrence of dementia, while the main independent variable was pain severity (none, little, somewhat, quite a bit, very). Depression score served as the mediating factor. Chi-square and binary logistic regression analyses were performed to examine the relationship between depression and the occurrence of pain and dementia. An intermediate model was constructed by stepwise regression. Results: The study indicates a significant association between cognitive impairment and both chronic pain and depressive symptoms in older adults living in China. Individuals who frequently report experiencing pain exhibit a higher likelihood of developing dementia when compared to those who do not report any pain (odds ratio (OR) = 1.72, p < 0.001). Moreover, depressive symptoms significantly mediate the relationship between pain and dementia, with the mediating effect accounting for 65.25%. Conclusions: Chronic pain not only directly impacts patients' cognitive function but also indirectly exacerbates cognitive impairment through depressive symptoms as a mediating variable. For elderly individuals experiencing depressive symptoms, it is important to provide appropriate psychological treatment in conjunction with pain management strategies. (AU)
Descriptores: dolor crónico/psicología
cognición
depresión/psicología
demencia/psicología
-China/epidemiología
Límites: seres humanos
masculino
femenino
anciano
ancianos de 80 o más años
Tipo de Publicación: informes de casos
Responsable: ES15.1 - BNCS


  10 / 1235 IBECS  
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Id: 232343
Autor: Chen, Guanru.
Título: Influencing Factors on the Efficacy of Aerobic Exercise Therapy in Depression: A Single-Centre Cross-Sectional Study
Fuente: Actas esp. psiquiatr;52(2):107-113, 2024. tab.
Idioma: en.
doi: 10.62641/aep.v52i2.1585.
Resumen: Background: Aerobic exercise therapy can improve brain function and promote positive emotions in patients with depression. This study aims to improve the efficacy of aerobic exercise therapy in depression by investigating the influencing factors therein.Methods: This study conducted a single-centre cross-sectional analysis of clinical data from 211 depression patients who received aerobic exercise therapy at Heze Mudan People's Hospital from May 2021 to May 2023. After excluding 10 patients who did not meet the inclusion criteria, the final cohort included 201 patients. The clinical data of patients with effective treatment and patients with ineffective treatment were collected, such as socio-demographic characteristics, disease status, depression degree, treatment compliance, and social support. Binary Logistic regression was used to analyze the factors affecting the clinical efficacy of aerobic exercise therapy in patients.Results: Among the 201 patients, the effective and ineffective rates of aerobic exercise therapy were 80.10% (161/201) and 19.90% (40/201), respectively. When analysed as groups, no significant differences were observed between the effective group (EG) and ineffective group (IG) regarding gender, body mass index, course of depression, age of first onset, mental symptoms, years of education, personal income, or marital status (p > 0.05). However, the EG exhibited a reduced probability of family history of mental illness, smoking history, and severity of depression (p < 0.05), along with higher treatment compliance and Social Support Rating Scale (SSRS) scores compared to the IG (p < 0.05). Binary logistic regression analysis revealed that smoking history, family history of mental illness, treatment compliance, depression, and SSRS score were the primary influencing factors on the efficacy of aerobic exercise therapy (p < 0.05). ... (AU)
Descriptores: ejercicio físico
tratamiento por actividad física/psicología
depresión/psicología
-resultado del tratamiento
estudios transversales
Límites: seres humanos
masculino
femenino
adulto
persona de mediana edad
Tipo de Publicación: informes de casos
Responsable: ES15.1 - BNCS



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